| Catalog# |
CI46 |
| Source |
Human Cells |
| Description |
Recombinant Human HACL1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Met578) of Human HACL1 fused with a polyhistidine tag at the C-terminus. |
| Names |
2-hydroxyacyl-CoA lyase 1, 2-hydroxyphytanoyl-CoA lyase, Phytanoyl-CoA 2-hydroxylase 2, HACL1, HPCL, HPCL2, PHYH2, HSPC279 |
| Accession # |
Q9UJ83 |
| Formulation |
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 |
| Shipping |
The product is shipped on dry ice/ice packs. |
| Storage |
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. |
| Purity |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Endotoxin |
Less than 0.1 ng/µg (1 IEU/µg). |
| Amino Acid Sequence |
MPDSNFAERSEEQVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACY AASAIGYLTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEA CRLYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVNLQVNVNSIKYMERCMSPPI SMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPY CVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNI HAVTKQLLEELDKTPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYYTVFYHVQEQLPR DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGD SAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQ VMTAFGGKGYFVQTPEELQKSLRQSLADTTKPSLINIMIEPQATRKAQDFHWLTRSNMVDHHHHH H
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| Background |
2-hydroxyacyl-CoA lyase 1 is a 115 amino acids protein that belongs to the TPP enzyme family.It is expressed in high levels in liver, also expressed in kidney, heart and skeletal muscle.It can catalyze a carbon-carbon cleavage reaction and cleave a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. |
