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C954
Recombinant Human EG-VEGF/PK1
10ug
1200
1080
现货
国产
-
C954
Recombinant Human EG-VEGF/PK1
50ug
3520
3168
现货
国产
-
C954
Recombinant Human EG-VEGF/PK1
500ug
12320
11088
现货
国产
-
C954
Recombinant Human EG-VEGF/PK1
1mg
17600
15840
现货
国产
-
C954
Recombinant Human PK1/EG-VEGF
10ug
1200
1080
现货
国产
-
C954
Recombinant Human PK1/EG-VEGF
50ug
3520
3168
现货
国产
-
C954
Recombinant Human PK1/EG-VEGF
500ug
12320
11088
现货
国产
-
C954
Recombinant Human PK1/EG-VEGF
1mg
17600
15840
现货
国产
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Catalog# C954 Source Human Cells Description Recombinant Human Pyruvate Kinase Isozymes R/L/PKLR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Ser574) of Human PKLR fused with a polyhistidine tag at the C-terminus. Names Pyruvate Kinase Isozymes R/L, Pyruvate Kinase 1, R-Type/L-Type Pyruvate Kinase, Red Cell/Liver Pyruvate Kinase, PKLR, PK1, PKL Accession # P30613 Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 2mM DTT,20% glycerol,pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQLPAAM ADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAES IANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRG NANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVD LPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDE ILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSD VANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVT AIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREP PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSISVDHHHHHHBackground Pyruvate Kinase Isozymes R/L (PKLR) belongs to the pyruvate kinase family, There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver; R is found in red cells; M1 is the main form in muscle, heart and brain; M2 is found in early fetal tissues. PKLR exists as a homotetramer and catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in PKLR are also the cause of pyruvate kinase deficiency of red cells, which is a frequent cause of hereditary non-spherocytic hemolytic anemia.