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C249
Recombinant Human PMM1/Phosphomannomutase 1
10ug
1200
1080
现货
国产
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C249
Recombinant Human PMM1/Phosphomannomutase 1
50ug
3520
3168
现货
国产
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C249
Recombinant Human PMM1/Phosphomannomutase 1
500ug
12320
11088
现货
国产
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C249
Recombinant Human PMM1/Phosphomannomutase 1
1mg
17600
15840
现货
国产
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Catalog# C249 Source E.coli Description Recombinant Human Phosphomannomutase 1/PMM1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala262) of Human PMM1 fused with a His tag at the C-terminus. Names Phosphomannomutase 1, PMM 1, PMMH-22, PMM1, PMMH22 Accession # Q92871 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MAVTAQAARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYCKIAEQLGD GDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLSYMALLRLPKKRGTFIE FRNGMLNISPIGRSCTLEERIEFSELDKKEKIREKFVEALKTEFAGKGLRFSRGGMISFDVFPEG WDKRYCLDSLDQDSFDTIHFFGNETSPGGNDFEIFADPRTVGHSVVSPQDTVQRCREIFFPETAH EAVEHHHHHHBackground Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the degradation of glucose-1,6 bisphosphate in ischemic brain.