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CE80

Recombinant Human PPP1CC/Protein phosphatase 1C catalytic subunit

10ug

1200

1080

现货

国产

CE80

Recombinant Human PPP1CC/Protein phosphatase 1C catalytic subunit

50ug

3520

3168

现货

国产

CE80

Recombinant Human PPP1CC/Protein phosphatase 1C catalytic subunit

500ug

12320

11088

现货

国产

CE80

Recombinant Human PPP1CC/Protein phosphatase 1C catalytic subunit

1mg

17600

15840

现货

国产

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  • Catalog# CE80
    Source E.coli
    Description Recombinant Human Serine/Threonine-Protein Phosphatase PP1-γ Catalytic Subunit/PPP1CC is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Lys323) of Human PPP1CC fused with a 6His tag at both the N-terminus and C-terminus.
    Names Serine/Threonine-Protein Phosphatase PP1-Gamma Catalytic Subunit, PP-1G, Protein Phosphatase 1C Catalytic Subunit, PPP1CC
    Accession # P36873
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREI FLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAY KIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGG LSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHD LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPN ATRPVTPPRGMITKQAKKLEHHHHHH
    Background Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1CC may play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.