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C163
Recombinant Human PPP1R1A/Protein phosphatase 1 regulatory subunit 1A/IPP-1
10ug
840
756
现货
国产
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C163
Recombinant Human PPP1R1A/Protein phosphatase 1 regulatory subunit 1A/IPP-1
50ug
2520
2268
现货
国产
-
C163
Recombinant Human PPP1R1A/Protein phosphatase 1 regulatory subunit 1A/IPP-1
500ug
12320
11088
现货
国产
-
C163
Recombinant Human PPP1R1A/Protein phosphatase 1 regulatory subunit 1A/IPP-1
1mg
17600
15840
现货
国产
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Catalog# C163 Source E.coli Description Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A/PPP1R1A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Val171) of Human PPP1R1A. Names Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1 Accession # Q13522 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MEQDNSPQKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLA MSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTS GTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSVLEHHHHHHBackground Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.