产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
CF42
Recombinant Human IR1B4/PRMT1
10ug
840
756
现货
国产
-
CF42
Recombinant Human IR1B4/PRMT1
50ug
2520
2268
现货
国产
-
CF42
Recombinant Human IR1B4/PRMT1
500ug
12320
11088
现货
国产
-
CF42
Recombinant Human IR1B4/PRMT1
1mg
17600
15840
现货
国产
-
CF42
Recombinant Human PRMT1/HMT2/HRMT1L2
10ug
840
756
现货
国产
-
CF42
Recombinant Human PRMT1/HMT2/HRMT1L2
50ug
2520
2268
现货
国产
-
CF42
Recombinant Human PRMT1/HMT2/HRMT1L2
500ug
12320
11088
现货
国产
-
CF42
Recombinant Human PRMT1/HMT2/HRMT1L2
1mg
17600
15840
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# CF42 Source E.coli Description Recombinant Human Protein Arginine N-Methyltransferase 1/PRMT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Arg343) of Human PRMT1 fused with a 6His tag at the N-terminus. Names Protein arginine N-Methyltransferase 1, Histone-arginine N-Methyltransferase PRMT1, Interferon Receptor 1-Bound Protein 4, PRMT1, HMT2, HRMT1L2, IR1B4 Accession # Q99873-3 Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRT LTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHV VTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAI EDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFT SPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFG TIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMBackground Protein Arginine N-Methyltransferase 1 (PRMT1) is a cytoplasmic protein that belongs to the protein arginine N-methyltransferase family. PRMT1 is a arginine methyltransferase that functions as a histone methyltransferase for H4. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes. PRMT1 methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. PRMT1 is responsible for the majority of cellular arginine methylation activity. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity in the late phase of interferon gamma (IFN-gamma) signaling. It may be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and serve as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.