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CH40

Recombinant Human RGMA/Repulsive guidance molecule A

10ug

640

576

现货

国产

CH40

Recombinant Human RGMA/Repulsive guidance molecule A

50ug

2000

1800

现货

国产

CH40

Recombinant Human RGMA/Repulsive guidance molecule A

500ug

12320

11088

现货

国产

CH40

Recombinant Human RGMA/Repulsive guidance molecule A

1mg

17600

15840

现货

国产

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  • Catalog# CH40
    Source E.coli
    Description Recombinant Human Repulsive guidance molecule A/RGM domain family member A is produced with our E. coli expression system. The target protein is expressed with sequence(Pro169-Gly422) of human RGMA fused with a His tag at the N-terminus.
    Names Repulsive guidance molecule A,RGM domain family member A,RGM
    Accession # Q96B86
    Formulation Supplied as a 0.2 μm filtered solution of PBS.pH7.4,1mMDTT
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MNHKVHHHHHHMPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFK NFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQV GRYLTFAVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTA PETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYER TRDLPG*
    Background Repulsive guidance molecule A(RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.