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CH40
Recombinant Human RGMA/Repulsive guidance molecule A
10ug
640
576
现货
国产
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CH40
Recombinant Human RGMA/Repulsive guidance molecule A
50ug
2000
1800
现货
国产
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CH40
Recombinant Human RGMA/Repulsive guidance molecule A
500ug
12320
11088
现货
国产
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CH40
Recombinant Human RGMA/Repulsive guidance molecule A
1mg
17600
15840
现货
国产
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Catalog# CH40 Source E.coli Description Recombinant Human Repulsive guidance molecule A/RGM domain family member A is produced with our E. coli expression system. The target protein is expressed with sequence(Pro169-Gly422) of human RGMA fused with a His tag at the N-terminus. Names Repulsive guidance molecule A,RGM domain family member A,RGM Accession # Q96B86 Formulation Supplied as a 0.2 μm filtered solution of PBS.pH7.4,1mMDTT Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MNHKVHHHHHHMPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFK NFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQV GRYLTFAVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTA PETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYER TRDLPG*Background Repulsive guidance molecule A(RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.