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C171
Recombinant Human Sentrin-specific protease 7/SSP2/SENP7
10ug
840
756
现货
国产
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C171
Recombinant Human Sentrin-specific protease 7/SSP2/SENP7
50ug
2520
2268
现货
国产
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C171
Recombinant Human Sentrin-specific protease 7/SSP2/SENP7
500ug
12320
11088
现货
国产
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C171
Recombinant Human Sentrin-specific protease 7/SSP2/SENP7
1mg
17600
15840
现货
国产
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Catalog# C171 Source E.coli Description Recombinant Human Sentrin-Specific Protease 7/SENP7 is produced by our E. coli expression system. The target protein is expressed with sequence (Met695-Ala864) of Human SENP7. Names Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2 Accession # Q9BQF6 Formulation Supplied as a 0.2 μm filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MKLKSVSQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGG LGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNP NLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLABackground Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.