产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
CA61
Recombinant Human SFRP-3/Secreted frizzled-related protein 3/FRZB
10ug
1200
1080
现货
国产
-
CA61
Recombinant Human SFRP-3/Secreted frizzled-related protein 3/FRZB
50ug
3520
3168
现货
国产
-
CA61
Recombinant Human SFRP-3/Secreted frizzled-related protein 3/FRZB
500ug
12320
11088
现货
国产
-
CA61
Recombinant Human SFRP-3/Secreted frizzled-related protein 3/FRZB
1mg
17600
15840
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# CA61 Source HEK293 Description Recombinant Human Secreted Frizzled-Related Protein 3/SFRP3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala33-Asn325) of Human SFRP3 fused with a polyhistidine tag at the C-terminus. Names Secreted Frizzled-Related Protein 3, sFRP-3, Frezzled, Fritz, Frizzled-Related Protein 1, FrzB-1, FRZB, FIZ, FRE, FRP, FRZB1, SFRP3 Accession # Q92765 Shipping The product is shipped at ambient temperature. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence AACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICT IDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPEAIVTADGADFP MDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKEIKTKCHDVTAVVEVKEILKSSL VNIPRDTVNLYTSSGCLCPPLNVNEEYIIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDMK LRHLGLSKSDSSNSDSTQSQKSGRNSNPRQARNVDHHHHHHBackground Secreted Frizzled-Related Protein 3 (sFRP-3) is a secreted protein that belongs to the secreted frizzled-related protein (sFRP) family. sFRP-3 contains one frizzled (FZ) domain and one NTR domain. sFRP-3 is highly expressed in placenta and heart, followed by brain, skeletal muscle, kidney and pancreas. It is also weakly detected in the lung and liver. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. sFRP-3 appears to be involved in limb skeletogenesis and antagonist of Wnt8 signaling. sFRP-3 also regulates chondrocyte maturation and long bone development. Defects in sFRP-3 are a cause of female-specific osteoarthritis (OA) susceptibility.