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CF35
Recombinant Human SH2D1A/SH2 domain-containing protein 1A
10ug
760
684
现货
国产
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CF35
Recombinant Human SH2D1A/SH2 domain-containing protein 1A
50ug
2000
1800
现货
国产
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CF35
Recombinant Human SH2D1A/SH2 domain-containing protein 1A
500ug
12320
11088
现货
国产
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CF35
Recombinant Human SH2D1A/SH2 domain-containing protein 1A
1mg
17600
15840
现货
国产
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Catalog# CF35 Source E.coli Description Recombinant Human SH2 Domain-Containing Protein 1A/SH2D1A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro128) of Human SH2D1A fused with a 6His tag at the N-terminus. Names SH2 Domain-Containing Protein 1A, Duncan Disease SH2-Protein, Signaling Lymphocytic Activation Molecule-Associated Protein, SLAM-Associated Protein, T-Cell Signal Transduction Molecule SAP, SH2D1A, DSHP, SAP Accession # O60880 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 10% Glycerol, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCV LYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARS TQGTTGIREDPDVCLKAPBackground SH2 Domain-Containing Protein 1A,(SH2D1A) contains one SH2 domain and a short tail and is localized in the cytoplasm. SH2D1A is expressed at a high level in the thymus and the lung, with lower expression levels in the spleen and the liver. SH2D1A acts as an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. In addition, SH2D1A mediates interaction between FYN and SLAMF1. It is also thought to regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.