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CC63
Recombinant Human SIL1/Nucleotide exchange factor SIL1
10ug
840
756
现货
国产
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CC63
Recombinant Human SIL1/Nucleotide exchange factor SIL1
50ug
2520
2268
现货
国产
-
CC63
Recombinant Human SIL1/Nucleotide exchange factor SIL1
500ug
12320
11088
现货
国产
-
CC63
Recombinant Human SIL1/Nucleotide exchange factor SIL1
1mg
17600
15840
现货
国产
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Catalog# CC63 Source HEK293 Description Recombinant Human Nucleotide exchange factor SIL1/SIL1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (His32-Arg461) of Human SIL1 fused with a polyhistidine tag at the C-terminus. Names Nucleotide exchange factor SIL1, also named BiP-associated protein, is a member of the SIL1 family. Accession # Q9H173 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence HQNLKEFALTNPEKSSTKETERKETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQ TGEREAKLQYEDKFRNNLKGKRLDINTNTYTSQDLKSALAKFKEGAEMESSKEDKARQAEVKRLF RPIEELKKDFDELNVVIETDMQIMVRLINKFNSSSSSLEEKIAALFDLEYYVHQMDNAQDLLSFG GLQVVINGLNSTEPLVKEYAAFVLGAAFSSNPKVQVEAIEGGALQKLLVILATEQPLTAKKKVLF ALCSLLRHFPYAQRQFLKLGGLQVLRTLVQEKGTEVLAVRVVTLLYDLVTEKMFAEEEAELTQEM SPEKLQQYRQVHLLPGLWEQGWCEITAHLLALPEHDAREKVLQTLGVLLTTCRDRYRQDPQLGRT LASLQAEYQVLASLELQDGEDEGYFQELLGSVNSLLKELRVDHHHHHHBackground Nucleotide exchange factor SIL1, also named BiP-associated protein, is a member of the SIL1 family. It is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. It is highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome.