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C885
Recombinant Human Sorbitol dehydrogenase/SORD
10ug
840
756
现货
国产
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C885
Recombinant Human Sorbitol dehydrogenase/SORD
50ug
2520
2268
现货
国产
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C885
Recombinant Human Sorbitol dehydrogenase/SORD
500ug
12320
11088
现货
国产
-
C885
Recombinant Human Sorbitol dehydrogenase/SORD
1mg
17600
15840
现货
国产
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Catalog# C885 Source Human Cells Description Recombinant Human Sorbitol Dehydrogenase/SORD is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala2-Pro357) of Human SORD fused with a polyhistidine tag at the C-terminus. Names Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD Accession # Q00796 Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,0.2M NaCl,5mM DTT,20% glycerol,pH8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence AAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPM VLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCR FYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMG AAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGI YATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRF PLEKALEAFETFKKGLGLKIMLKCDPSDQNPVDHHHHHHBackground Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.