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CG46
Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9
10ug
760
684
现货
国产
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CG46
Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9
50ug
2280
2052
现货
国产
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CG46
Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9
500ug
12320
11088
现货
国产
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CG46
Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9
1mg
17600
15840
现货
国产
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Catalog# CG46 Source E.coli Description Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Val298) of Human SDCBP/Syntenin-1 fused with a 6His tag at the C-terminus. Names 'Syntenin-1, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1,Syndecan-binding protein 1, SDCBP, MDA9, SYCL,' Accession # O00560 Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence SLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEI RANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKS IDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFE RTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTS GTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEVLEHHHHHHBackground Syntenin-1 is a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.