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C356
Recombinant Human HAVCR2/TIM-3
10ug
560
504
现货
国产
-
C356
Recombinant Human HAVCR2/TIM-3
50ug
1680
1512
现货
国产
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C356
Recombinant Human HAVCR2/TIM-3
500ug
12320
11088
现货
国产
-
C356
Recombinant Human HAVCR2/TIM-3
1mg
17600
15840
现货
国产
-
C356
Recombinant Human TIM-3/HAVCR2/TIMD3
10ug
560
504
现货
国产
-
C356
Recombinant Human TIM-3/HAVCR2/TIMD3
50ug
1680
1512
现货
国产
-
C356
Recombinant Human TIM-3/HAVCR2/TIMD3
500ug
12320
11088
现货
国产
-
C356
Recombinant Human TIM-3/HAVCR2/TIMD3
1mg
17600
15840
现货
国产
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Catalog# C356 Source HEK293 Description Recombinant Human T-Cell Membrane Protein 3/TIM-3 produced by transfected human cells is a secreted protein with sequence (Ser22-Arg200) of Human TIM3 fused with a polyhistidine tag at the C-terminus. Names Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T-Cell Immunoglobulin and Mucin Domain-Containing Protein 3, TIMD-3, T-Cell Membrane Protein 3, TIM-3, HAVCR2, TIM3, TIMD3 Accession # Q8TDQ0 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence SEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNG DFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTLQRDFTAAFPRM LTTRGHGPAETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIRVDHHHHHHBackground T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.