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C192

Recombinant Human Serpin A12

10ug

840

756

现货

国产

C192

Recombinant Human Serpin A12

50ug

2520

2268

现货

国产

C192

Recombinant Human Serpin A12

500ug

9840

8856

现货

国产

C192

Recombinant Human Serpin A12

1mg

14080

12672

现货

国产

C192

Recombinant Human Vaspin/SERPINA12

10ug

840

756

现货

国产

C192

Recombinant Human Vaspin/SERPINA12

50ug

2520

2268

现货

国产

C192

Recombinant Human Vaspin/SERPINA12

500ug

9840

8856

现货

国产

C192

Recombinant Human Vaspin/SERPINA12

1mg

14080

12672

现货

国产

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  • Catalog# C192
    Source E.coli
    Description Recombinant Human Serpin A12 is produced by our E. coli expression system. The target protein is expressed with sequence (Leu21-Lys414) of Human Serpin A12 fused with a GST tag at the N-terminus.
    Names Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, Visceral Adipose-Specific Serpin, SERPINA12
    Accession # Q8IW75
    Formulation Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 160mM NaCl, 0.2mM PMSF, 1mM DTT, 10% Glycerine, pH 7.2
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKL TQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEML KMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKS SKYIAWPLQGWQATFGGGDHPPKSDLVPRGSLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMD LGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYI IHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQK THGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQV GYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMT GTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPME TPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK
    Background Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.