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CG60
Recombinant Human ZNRF1/E3 ubiquitin-protein ligase ZNRF1
10ug
1200
1080
现货
国产
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CG60
Recombinant Human ZNRF1/E3 ubiquitin-protein ligase ZNRF1
50ug
3520
3168
现货
国产
-
CG60
Recombinant Human ZNRF1/E3 ubiquitin-protein ligase ZNRF1
500ug
13440
12096
现货
国产
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CG60
Recombinant Human ZNRF1/E3 ubiquitin-protein ligase ZNRF1
1mg
19200
17280
现货
国产
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Catalog# CG60 Source E.coli Description Recombinant Human ZNRF1/E3 ubiquitin-protein ligase ZNRF1 is produced with our E. coli expression system. The target protein is expressed with sequence (Pro74-Thr178) of Human ZNRF1 fused with a 6His tag at the N-terminus and C-terminus. Names E3 ubiquitin-protein ligase ZNRF1, nerve injury-induced gene 283 protein, zinc/ring finger protein 1, NIN283, ZNRF1 Accession # Q8ND25 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.15M NaCl,1mM EDTA,10%glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMPASRGTGDSERAPGGGGSASDSTYAHGNGYQETGGGHHRDGMLY LGSRASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTLEHH HHHH*Background E3 ubiquitin-protein ligase ZNRF1 contains one ring-type zinc finger, high expressed in the nervous system and developing brain, low expressed in testis and thymus. ZNRF1 mediates the ubiquitination of AKT1 and GLUL, so it plays a role in neuron cells differentiation. It also has a role in the establishment and maintenance of neuronal transmission and plasticity. ZNRF1 regulates Schwann cells differentiation by mediating ubiquitination of GLUL.